教育學院
Permanent URI for this communityhttp://rportal.lib.ntnu.edu.tw/handle/20.500.12235/1
教育學院成立於民國44年6月5日，時值臺灣省立師範學院改制為臺灣省立師範大學，初設教育、社會教育、體育衛生教育、家政教育、工業教育五個學系，發展迄今，本院共設有7個學系（均含學士、碩士及博士班）、5個獨立研究所、1個院級在職碩士專班。
本院為國內歷史最久之教育學院，系所規模、師資，及學生品質向為國內首屈一指，培育英才無數，畢業校友或擔任政府教育行政單位首長及中堅人才、或為大學校長及教育相關領域研究人員、或為國內中等教育師資之骨幹、或投入民間文教事業相關領域，皆為提升我國教育品質竭盡心力。此外，本學院長期深耕學術，研究領域多元，發行4本 TSSCI 期刊，學術聲望備受國內外學界肯定，根據 2015 年 QS 世界大學各學科排名結果，本校在教育學科名列第22名，不僅穩居臺灣第一，更躍居亞洲師範大學龍頭。
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Item 素食停經婦女體內Isoflavones與DHA狀態之探討(2002) 王翠芬為探討素食者體內異黃酮與DHA狀態及對健康之影響，在台北地區招募身體健康、無高血脂且無使用荷爾蒙之葷食停經婦女26位，與素食停經婦女39位，進行實驗一：比較葷食與素食停經婦女血漿異黃酮狀態(daidzein 與 genistein)及尿液雌激素代謝物(2-hydroxyestrone，2OHE1 ; 16α-hydroxyestrone，16αOHE1) 排出，及兩者之相關性，結果顯示素食者血漿中daidzein 與 genistein皆明顯比葷食者高，反應了素食者黃豆製品攝取量確實高於葷食者。素食者尿液中2OHE1/creatinine以及2OHE1/16αOHE1 比值皆明顯較葷食者高，而血漿中daidzein含量與尿液中2OHE1/16αOHE1 比值有顯著正相關(R=0.53, p=0.004)，與16αOHE1/creatinine有負相關，但未達統計上的顯著意義(R=-0.318，p=0.108)，因此推論素食停經婦女雌激素代謝途徑傾向較低致癌性，且可能是受到飲食中高異黃酮攝取的影響。 實驗二以素食停經婦女為對象，評估補充DHA後，對其心臟血管疾病危險因子之影響，首先依據素食停經婦女血中三酸甘油酯與膽固醇含量分為正常血脂者(＜200 mg/dl)與血脂偏高者(≧200 mg/dl)，所有素食者每日服用6 ml安慰劑(corn oil)，經過2週適應期(run-in)後，，正常血脂者一半補充corn oil (6 ml/d)為placebo (normal)組(n=12)，另一半補充來自藻類的DHA oil (6 ml/d，2.1 g DHA)為DHA (normal)組（n=12），血脂偏高者皆補充DHA oil (6 ml/d，2.1 g DHA)為DHA (hyperlipidemic)組(n=9)。於六週實驗期前後收集共兩次血液與尿液樣本。結果顯示補充DHA 後，DHA (normal)組LDL氧化1小時、2小時與3小時之TBARS產生量增加，且血漿中α-tocopherol含量明顯下降，而DHA (hyperlipidemic)組尿液中nitric oxide濃度高於補充前。DHA補充後normal組與hyperlipidemic組LDL中DHA含量明顯增加，placebo組則不變。血漿中總抗氧化狀態、lipoprotein(a)、以及尿液中F2α-isoprostane 含量不受DHA補充影響。整體來看，素食停經婦女補充DHA會使體外LDL氧化增加但對體內氧化壓力無明顯改變，對於血脂質則無明顯好處，唯可增加血脂偏高的素食停經婦女nitric oxide生成，因此，本研究僅發現補充DHA對於素食停經婦女的心臟血管疾病危險因子的微小影響。Item Effects of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women(Nature Publishing Group, 2006-03-01) Wu WH, Lu SC, Wang TF, Jou HJ, Wang TABackground: Vegetarians are generally deficient in long-chain n-3 fatty acids. Long-chain n-3 fatty acids have a beneficial effect on plasma lipid levels, and some studies showed that they had breast cancer suppression effect. One of the biomarkers of breast cancer risk is the ratio of urinary 2-hydroxyestrone (2-OHE1) to 16-hydroxyestrone (16-OHE1). Objective: To investigate the effect of docosahexaenoic acid (DHA, 22:6n-3) supplementation on blood lipids, estrogen metabolism and oxidative stress in vegetarians. Design: Single-blind, randomized, placebo-controlled trial. Interventions: Twenty-seven postmenopausal vegetarian women were recruited. After a 2-week run-in period with 6 g placebo corn oil, the subjects were subsequently randomized to receive either 6 g corn oil (n=13) or 6 g DHA-rich algae oil (2.14 g of DHA/day) (n=14) for 6 weeks. Two subjects in corn oil group withdrew before completion. Main outcome measures: Plasma lipids, urinary 2-OHE1 and 16-OHE1, urinary F2-isoprostanes and plasma -tocopherol. Results: Plasma LDL-DHA and EPA level increased significantly by DHA supplementation. DHA decreased plasma cholesterol (C) levels (P=0.04), but did not influence the levels of plasma TG, LDL-C and HDL-C, -tocopherol, urinary F2-isoprostanes, 2-OHE1, 16-OHE1 and ratio of 2-OHE1 to 16-OHE1 as compared to corn oil. Conclusion: DHA supplementation at a dose of 2.14 g/day for 42 days decreases plasma cholesterol but neither does it show beneficial effects on estrogen metabolism, nor does it induce deleterious effects on the observed in vivo antioxidant or oxidative stress marker in postmenopausal vegetarian women.