Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticles

dc.contributor國立臺灣師範大學化學系zh_tw
dc.contributor.authorC.-L. Chenen_US
dc.contributor.authorL.-R. Kuoen_US
dc.contributor.authorS.-Y. Leeen_US
dc.contributor.authorY.-K. Hwuen_US
dc.contributor.authorS.-W. Chouen_US
dc.contributor.authorChia-Chun Chenen_US
dc.contributor.authorF.-H. Changen_US
dc.contributor.authorK.-H. Linen_US
dc.contributor.authorD.-H. Tsaien_US
dc.contributor.authorY.-Y. Chenen_US
dc.date.accessioned2014-12-02T06:41:38Z
dc.date.available2014-12-02T06:41:38Z
dc.date.issued2013-01-01zh_TW
dc.description.abstractFePt nanoparticles (NPs) have recently been revealed to be significant multifunctional materials for the applications of biomedical imaging, drug delivery and magnetic hyperthermia due to their novel magnetic properties. In this study, a newly discovered photothermal effect activated by the near infrared (NIR) femtosecond laser for FePt NPs was demonstrated. The threshold laser energy to destroy cancer cells was found to be comparable to that of gold nanorods (Au NRs) previously reported. Through the thermal lens technique, it was concluded that the temperature of the FePt NPs can be heated up to a couple of hundreds degree C in picoseconds under laser irradiation due to the excellent photothermal transduction efficiency of FePt NPs. This finding boosts FePt NPs versatility in multifunctional targeted cancer therapy.en_US
dc.description.urihttp://ac.els-cdn.com/S0142961212011799/1-s2.0-S0142961212011799-main.pdf?_tid=9faeb7aa-b2fd-11e3-8514-00000aab0f01&acdnat=1395628992_ec284dda83dbe5e482fc7d4d87bf1846zh_TW
dc.identifierntnulib_tp_C0301_01_087zh_TW
dc.identifier.issn0142-9612zh_TW
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw/handle/20.500.12235/42371
dc.languageen_USzh_TW
dc.publisherElsevieren_US
dc.relationBiomaterials, 34(4), 1128-1134.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.biomaterials.2012.10.044zh_TW
dc.subject.otherPhotothermal therapyen_US
dc.subject.otherFePten_US
dc.subject.otherNanoparticleen_US
dc.subject.otherCancer therapyen_US
dc.subject.otherThermal lensen_US
dc.subject.otherLaseren_US
dc.titlePhotothermal cancer therapy via femtosecond-laser-excited FePt nanoparticlesen_US

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