Preparation of Fluorescent Silica Nanotubes and their Application in Gene Delivery
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Date
2005-02-01
Authors
Chia-Chun Chen
Y.-C. Liu
C.-H. Wu
C.-C. Yeh
M.-T. Su
Y.-C. Wu
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley-VCH Verlag
Abstract
Fluorescent silica nanotubes are synthesized through a sol–gel reaction using an anodic aluminum oxide membrane template. The nanotubes are filled with plasmid DNA encoding green fluorescence protein (GFP), which are incorporated into mammalian cells that subsequently express GFP (see Figure). The results demonstrate a novel application of nanotubes in biomolecule delivery.