有無規律有氧運動健康老年男性脈波傳導速率、C-反應蛋白及心肺適能之比較

Abstract

本研究目的在於比較有無規律運動老年男性脈波傳導速率(PWV)、C-反應蛋白濃度(CRP)、心肺適能及在CRP與PWV相對危險等級的差異性。 本研究以54位年齡在65-75歲的健康老年男性為研究對象，其中規律運動組27人以及無規律運動組組27人。受試者經篩選排除有抽菸或嚴重心血管疾病、高血壓、糖尿病以及腎臟病症狀者後，填寫同意書後進行血壓、安靜時PWV、CRP及六分鐘走路測驗。相對危險等級的分類PWV以所有受試者的中數為主，高於中數者為高危險等級；而CRP的分類則採取美國心臟病協會認定標準分為低、中、高危險等級。獨立樣本t考驗比較各變項的差異，卡方考驗有無規律運動在PWV及CRP相對危險等級的差異性，顯著水準α=.05。研究結果如下： (一) 規律運動組的六分鐘走路測驗成績明顯高於非規律運動組 (565.30 ± 74.13公尺 vs. 484.15 ± 125.93公尺, P<.05)。 (二) 規律運動組擁有較低PWV(13.05 ± 2.66 m/s vs 14.64 ± 3.77 m/s)的傾向，且有較高比例的受試者屬於PWV低危險等級(35.2% 比 16.7%，p <.05)。 (三) 規律運動組不但擁有較低的CRP濃度(0.13 ± 0.12 mg/dL vs 0.22 ± 0.18 mg/dL, p<.05)，而且有較高比例的受試者屬於CRP的低危險等級(31.5% 比18.5%，p <.05)。 結論：有從事規律有氧運動習慣的老年人，其心肺適能、脈波傳導速率與C-應蛋白濃度均優於無規律運動者，且其相對危險等級也較低。

The purposes of this study were to investigate the differences of pulse wave velocity (PWV), the level of C-reactive protein (CRP), and cardiopulmonary fitness (CF) between regular (RG) and non-regular (Non-RG) of elder males; and compare the difference the risk factor level by PWV and CRP between RG and Non-RG. Fifty four elder healthy male volunteers (excluded subjects with smoking or severe cardiovascular, end-stage renal disease, hypertension, and diabetic symptoms) were recruited including regular exercise subjects and none regular exercise subjects. After the subjects signed consent, static blood pressure, PWV, CRP and 6-min walking test were measured. The blood sample was obtained to determined CRP. Three relative risk (RR) levels of concentration of CRP were classified by American Heart Association (AHA), and two RR levels of PWV were sorted by the median value of whole samples. Independent-t tests were used to test the differences between two groups on all the variables, and Chi square (χ2) were used to analyze the difference of the risk factor level by PWV and CRP between two groups. The statistical significant level was set at .05. The findings were as follows. 1. RG had significant better (p<.05) 6-min walking test score than Non-RG (565.30 ± 74.13 vs 484.15 ± 125.93 m) 2. RG had tendency lower of PWV (13.05 ± 2.66 m/s vs 14.64 ± 3.77 m/s) and lower relative risk level of PWV than Non-RG (low RR was 35.2% vs 16.7%, p<.05). 3. CRP of RG was significantly lower than that of Non-RG (0.13 ± 0.12 mg/dL vs 0.22 ± 0.18 mg/dL, p<.05), and relative risk level of CRP was lower than Non-RG, too(low RR was 31.5% vs 18.5%, p<.05). In conclusion, participation regular aerobic exercise has high level of cardiopulmonary functions and has lower relative risk level of CRP and PWV for elder people.